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A 64 year old male presents to the emergency department complaining of crushing pressure like chest pain, radiating to his left arm and neck which started 3 hours prior. The pain is worse than his typical angina and is not relieved by nitroglycerin. You contact his PMD, who informs you that he had a stent placed last year, as well as a PMH of DM, HTN, diabetic retinopathy, and a small cerebral infarct 9 months ago. He also reports that the patients’ EKG last week was normal which you confirm by fax. Cardiology and cardiac catheterization are not available. CXR and physical exam are normal.
What does the EKG show and what is the diagnosis?
Rate: 54
Rhythm: sinus bradycardia
Axis: left axis
PR: normal
QRS: wide
ST: T inversion in I, AVL, V3-V6
EKG diagnosis: Sinus bradycardia with LBBB
Clinical diagnosis: Sinus bradycardia with a new LBBB, most likely secondary to acute myocardial infarction
Treatment: Aspirin, nitroglycerin, oxygen, morphine (MONA)
-Hold beta blockers secondary to bradycardia
-consider giving heparin and IIb/IIIa inhibitor
-Do not thrombolyse due to history of CVA within past year
What are the indications for thrombolysis (specifically time to treatment, ST elevation height and EKG changes)?
-Less than 6-12 hours of symptom onset
-Symptoms compatible with acute MI
-EKG changes with:
- -At least 1 mm ST segment elevation in two or more contiguous leads
- -OR new LBBB
What are the five “absolute contraindications” to thrombolysis (as per Tintinalli)?
-Previous hemorrhagic stroke at any time
-Any CVA in the past year
-Known intracranial neoplasm
-Active internal bleeding (excluding menses)
-Suspected aortic dissection or pericarditis
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